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Table 2 Type 1 error and power of data sets of simulation 2

From: Principal-component-based multivariate regression for genetic association studies of metabolic syndrome components

LD (r)

PCBMR

Single-Trait Association

 

GEN

ADD

DOM

REC

GEN

ADD

DOM

REC

0

5

4.2

4.6

5.5

5.8(2.5)

5.3(3.1)

5.7(3.1)

5.7(3.1)

0.1

4.1

4.8

5.3

4.7

5.5(2.8)

6.0(3.4)

6.6(3.9)

5.2(2.7)

0.2

9.2

11

10.1

8.2

9.9(5.4)

12.3(6.5)

10.2(6.3)

8.0(4.3)

0.3

14.8

19.6*

16.2*

11.7

14.0(8.1)

17.5(10.5)

14.6(8.4)

10.4(6.2)

0.4

18.7*

24.3*

20.5*

11.7

15.9(10.2)

19.6(11.9)

16.5(10.7)

10.4(6.2)

0.5

26.6*

32.9*

29.7*

11.7

20.1(13.8)

23.8(17.4)

23.4(15.9)

10.4(6.2)

0.6

50.2*

62.8*

56.2*

26.6*

36.6(27.9)

47.0(36.3)

41.4(31.2)

21.2(13.8)

0.7

49.2*

61.6*

56.1*

23.4*

36.7(27.2)

46.8(34.6)

40.6(29.4)

20.7(12.5)

0.8

72.6*

81.5*

76.7*

37.6*

52.0(42.3)

63.1(52.2)

57.2(46.0)

27.9(18.9)

0.9

80.8*

89.7*

86.2*

37.6*

62.0(50.4)

71.9(62.2)

67.9(57.0)

27.9(18.9)

1

91.4*

95.2*

92.8*

48.9*

72.8(62.8)

82.0(73.4)

76.7(67.3)

36.7(27.0)

  1. (See Table 1)