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Table 6 Epistatic model - dominant (EPI DD).

From: Neural networks for modeling gene-gene interactions in association studies

 

Low risk

High risk

 

r1 = 2; r2 = 4

r1 = 5; r2 = 10

Theoretical penetrance matrix

Neural network

  

   Mean absolute difference E

   Sum

0.3095

0.2524

Logistic regression

  

   Mean absolute difference E

   Sum

0.3132

0.6528

Logistic regression (design variables)

  

   Mean absolute difference E

   Sum

0.3071

0.2648

  1. Mean absolute differences between theoretical and estimated penetrance matrices from 100 replications in the low and high risk scenario.
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