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Table 4 Multiplicative model (MULT).

From: Neural networks for modeling gene-gene interactions in association studies

  Low risk High risk
  a1 = 2· a0; a2 = 4· a0 a1 = 5· a0; a2 = 10· a0
  b1 = 5· b0; b2 = 10· b0 b1 = 5· b0; b2 = 10· b0
Theoretical penetrance matrix
Neural network   
   Mean absolute difference E
   Sum 0.2428 0.2178
Logistic regression   
   Mean absolute difference E
   Sum 0.3965 0.4887
Logistic regression (design variables)   
   Mean absolute difference E
   Sum 0.1637 0.1833
  1. Mean absolute differences between theoretical and estimated penetrance matrices from 100 replications in the low and high risk scenario.