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Table 1 P-values from Fisher's exact test calculated for the four viral isolates showing patterns of A to G hypermutations.

From: Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae)

 

Mutated As

Unmutated As

Viral isolate

preferred site*

unpreferred site**

preferred site

unpreferred site

p -value

A3 E55

20

0

89

32

0.007

DM113

20

0

16

11

0.001

U125

4

1

1

5

0.08

Derby

5

0

8

7

0.114

  1. *preferred sites for ADAR-induced hypermutations are As that are preceded by either an A, U or C.
  2. **unpreferred sites for ADAR-induced hypermutations are As that are preceded by a G.
  3. ***unmutated sites are defined as As within the cluster of mutations that have not been mutated.