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Table 5 Power of global test via 1500 simulations at α = 0.05

From: Regression-based approach for testing the association between multi-region haplotype configuration and complex trait

Sample Size

Disease Allele Frequency

Model Type

  

Model 3

Model 4

Model 7

Model 8

50

q = 0.1

0.977

0.824

0.947

0.478

 

q = 0.3

0.964

0.920

0.968

0.891

 

q = 0.5

0.947

0.625

0.596

0.741

100

q = 0.1

0.934

0.936

0.952

0.937

 

q = 0.3

0.979

0.957

0.941

0.889

 

q = 0.5

0.965

0.836

0.917

0.887

200

q = 0.1

0.978

0.963

0.968

0.916

 

q = 0.3

0.968

0.972

0.968

0.967

 

q = 0.5

0.967

0.971

0.954

0.960

400

q = 0.1

0.968

0.967

0.948

0.944

 

q = 0.3

0.971

0.947

0.974

0.920

 

q = 0.5

0.948

0.958

0.967

0.962