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Table 3 Power of three models via 1500 simulations at α = 0.05

From: Regression-based approach for testing the association between multi-region haplotype configuration and complex trait

Sample Size

Disease Allele Frequency

Model Type

  

hapcc

htr

HAPGLM

50

q = 0.1

0.947

0.947

0.947

 

q = 0.3

0.866

0.907

0.968

 

q = 0.5

0.666

0.391

0.596

100

q = 0.1

0.977

0.971

0.952

 

q = 0.3

0.963

0.927

0.941

 

q = 0.5

0.834

0.728

0.917

200

q = 0.1

0.980

0.980

0.968

 

q = 0.3

0.981

0.981

0.968

 

q = 0.5

0.961

0.912

0.954

400

q = 0.1

0.967

0.981

0.948

 

q = 0.3

0.981

0.983

0.974

 

q = 0.5

0.934

0.925

0.967