BMC Genomic Data

Table 1 Step 1: Summary descriptive statistics of the average maximum NPL LOD scores and the average IC with ungenotyped parents.

From: Handling linkage disequilibrium in qualitative trait linkage analysis using dense SNPs: a two-step strategy

		2 affected sibs		3 affected sibs		4 affected sibs
	Ave # SNPs	MLS (SD)	IC	MLS (SD)	IC	MLS (SD)	IC
Unadjusted	6012	13.27 (2.77)	0.72	14.41 (3.64)	0.80	7.86 (2.20)	0.84
MAF ≥ 0.05	5387	13.49 (2.66)	0.72	14.77 (3.64)	0.80	8.06 (2.23)	0.84
MAF ≥ 0.10	4616	13.87 (2.64)	0.72	15.00 (3.61)	0.80	8.18 (2.25)	0.84
MAF ≥ 0.20	3203	15.01 (2.69)	0.72	15.47 (3.61)	0.79	7.90 (2.42)	0.84
r² ≥ 0.95	4596	5.47 (1.79)	0.72	4.93 (2.06)	0.80	2.96 (1.55)	0.85
MAF ≥ 0.05 & r² ≥ 0.95	3713	9.62 (2.75)	0.72	14.01 (3.43)	0.80	5.02 (1.95)	0.85

Back to article page

ISSN: 2730-6844

Contact us

General enquiries: journalsubmissions@springernature.com