TY - JOUR AU - Hardin, Jill AU - Finnell, Richard H. AU - Wong, David AU - Hogan, Michael E. AU - Horovitz, Joy AU - Shu, Jenny AU - Shaw, Gary M. PY - 2009 DA - 2009/07/22 TI - Whole genome microarray analysis, from neonatal blood cards JO - BMC Genetics SP - 38 VL - 10 IS - 1 AB - Neonatal blood, obtained from a heel stick and stored dry on paper cards, has been the standard for birth defects screening for 50 years. Such dried blood samples are used, primarily, for analysis of small-molecule analytes. More recently, the DNA complement of such dried blood cards has been used for targeted genetic testing, such as for single nucleotide polymorphism in cystic fibrosis. Expansion of such testing to include polygenic traits, and perhaps whole genome scanning, has been discussed as a formal possibility. However, until now the amount of DNA that might be obtained from such dried blood cards has been limiting, due to inefficient DNA recovery technology. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-10-38 DO - 10.1186/1471-2156-10-38 ID - Hardin2009 ER -