TY - JOUR AU - Moe, Maren AU - Lien, Sigbjørn AU - Aasmundstad, Torunn AU - Meuwissen, Theo HE AU - Hansen, Marianne HS AU - Bendixen, Christian AU - Grindflek, Eli PY - 2009 DA - 2009/07/05 TI - Association between SNPs within candidate genes and compounds related to boar taint and reproduction JO - BMC Genetics SP - 32 VL - 10 IS - 1 AB - Boar taint is an unpleasant odour and flavour of the meat from some uncastrated male pigs primarily caused by elevated levels of androstenone and skatole in adipose tissue. Androstenone is produced in the same biochemical pathway as testosterone and estrogens, which represents a particular challenge when selecting against high levels of androstenone in the breeding programme, without simultaneously decreasing levels of other steroids. Detection of single nucleotide polymorphisms (SNPs) associated with compounds affecting boar taint is important both for gaining a better understanding of the complex regulation of the trait and for the purpose of identifying markers that can be used to improve the gain of breeding. The beneficial SNPs to be used in breeding would have the combinational effects of reducing levels of boar taint without affecting fertility of the animals. The aim of this study was to detect SNPs in boar taint candidate genes and to perform association studies for both single SNPs and haplotypes with levels of boar taint compounds and phenotypes related to reproduction. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-10-32 DO - 10.1186/1471-2156-10-32 ID - Moe2009 ER -