Figure 4
From: Disentangling molecular relationships with a causal inference test
Four causal inference strategies, CC, CIT, BNC, and AIC were applied to simulated data under five distinct causal models, A-E, shown above. Here a genotype marker at a specific locus is denoted by L, a gene corresponding to measured transcript abundance is denoted by G, and a measured clinical trait is denoted by T. H denotes an unmeasured molecular trait.