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Figure 3 | BMC Genetics

Figure 3

From: Novel mutations in TLR genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection

Figure 3

Comparative amino acid sequences of human and sheep LRR motifs of TLR1 and TLR4. A (TLR1) and B (TLR4). Irregularities in the LRR motifs (LxxLxLxxNxL) are depicted with underlined letters; differences between human and ovine LRR domains are indicated with the dark ovals and mutations TLR1- Ser150Gly and Val220Met are highlighted with the dark squares. Known mutations in human TLR4 – Asp299Gly and Thr399Ile are located in extra LRR motif (*, B).

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BMC Genomic Data

ISSN: 2730-6844

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