A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines

BMC Genomic Data

Table 1 Mice from lethal lines produced in the chromosome 4 screen

Line Name	MGI Accession #	# homozygous balancer (dark brown)	# heterozygous mutants (light brown)	# homozygous mutants (white)	Chi-square probability (p)
l4Jus19	MGI:3033989	29	57	0	p < 0.001
l4Jus22	MGI:3038760	40	88	0	p < 0.001
l4Jus23	MGI:3043664	18	56	0	p < 0.001
l4Jus24	MGI:3043665	39	102	0	p < 0.001
l4Jus25	MGI:3046735	46	56	2	p < 0.001
l4Jus26	MGI:3577468	38	83	0	p < 0.001
l4Jus27	MGI:3577469	34	71	0	p < 0.001
l4Jus28	MGI:3577470	30	65	0	p < 0.001
l4Jus29	MGI:3577471	24	40	2	p < 0.001
l4Jus30	MGI:3577472	15	27	4	p < 0.04
l4Jus31	MGI:3577474	40	82	17	p < 0.002

The genotypes of progeny resulting from intercrosses between animals heterozygous for both the lethal mutation and the balancer are shown. Genotypes were determined at weaning by coat color, and a chi-square analysis was performed for each line to determine if the observed genotype ratio was statistically different from the expected Mendelian ratio.

ISSN: 2730-6844